Intention-To-Treat (ITT) vs. Per Protocol (PP) analysis in clinical trials
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Frank Harrell on Twitter: "@EpiEllie @_MiguelHernan @PCORI @HarvardChanSPH @US_FDA @PRECIS_2 @HarvardEpi I'd guess that pragmatic clinical trials do and should rely on intention to treat even more than non-pragmatic ones." / Twitter
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PDF] Per-Protocol Analyses of Pragmatic Trials. | Semantic Scholar
3- Intention to treat analysis vs. per-protocol analysis - YouTube
Screening: the information individuals need to support their decision: per protocol analysis is better than intention-to-treat analysis at quantifying potential benefits and harms of screening | BMC Medical Ethics | Full Text
